We offer you a new reagent for the diagnosis of monoclonal gammopathy - light Kappa chains of immunoglobulins:
Free light chains of monoclonal immunoglobulins are an important diagnostic marker of monoclonal gammopathy.
Monoclonal gammopathy or paraproteinemia is the collective name of a whole class of diseases in which there is a pathological secretion of abnormal, altered in chemical structure, molecular weight or immunological properties of immunoglobulins (gamma globulins) by one clone of plasma cells or B-lymphocytes. These immunoglobulins then disrupt the functions of certain organs and systems, such as the kidneys, which leads to the development of symptoms.
There are two types of immunoglobulin light chains: 1 kappa and 2 lambda. Serum concentrations of kappa and lambda light chains depend on the balance between plasma cell production and renal clearance.
In the case of plasma proliferative disorders, there is a secretion of excess monoclonal immunoglobulins or free light chains of immunoglobulins, which disrupts the normal balance between the kappa and lambda chains. The very kappa / lambda ratio that goes beyond is evidence of monoclonal gammopathy.
Reagents from the Spanish manufacturer BioSystems are ideal for routine laboratory diagnosis of monoclonal gammopathy!
◾️ Bireagent method;
◾️ Shelf life up to 3 years, even in the open!
◾️ High sensitivity - only 5.05 mg/dl = 0.05 g/l;
◾️ Wide measuring range from 5.05 to 1000 mg/dL = from 0.05 to 10.0 g/l;
◾️ High accuracy of analysis;
◾️ Meets European norms and standards;
◾️ You can download the SDS product safety data sheet at https://www.biosystems.es
To detect monoclonal gammopathy, we diagnose together with Medigran!